Cheap amoebic dysentery drug 'promising' - BBC News

It showed that auranofin was much better than the current treatment, metronidazole, at killing Entamoeba histolytica. Follow-up experiments showed that it was also more effective at treating mice and hamsters which had been infected with the ameoba.

Inexpensive arthritis drug may treat dysentery, giardiasis - Los Angeles Times

The current treatment for both is the antibiotic metronidazole, which has side effects that include nausea, vomiting, dizziness and headache. A team headed by Dr. James McKerrow, a pathologist at UC San Diego, and parasitologist Anjan Debnath of ...

Cheap arthritis drug effective against killer amoebic parasites that infect 50 million a year - New York Daily News

The experiments suggest auranofin would be 10 times more effective than metronidazole, the current medication for amoebic infection, which means that it could be used in very small doses or even as a one-off tablet. Better still, the drug has ...

A New Way to Kill Amoebas, From An Old Drug - Corante

They did have a good positive control, though - the nitroimidazole drug metronidazole, which is the only agent approved currently against the parasite (and to which it's becoming resistant). A screen of nearly a thousand known drugs and ...

Arthritis drug could also help combat major cause of dysenteric death worldwide - Newstrack India

It is listed by the National Institutes of Health as a category B priority biodefense pathogen. Current treatment relies on metronidazole, which has adverse effects, and potential resistance to the drug is an increasing concern. "Because ...

Dysentery May Be Treatable With Cheap Arthritis Drug - Medical News Today

Using a high-throughput drug screen he and his colleagues found that auranofin was 10 times more potent against the parasite Entamoeba histolytica than the current treatment metronidazole. They said their study illustrates the importance of ...

Arthritis Drug Effective Against Amoebic Parasites - Med India

The experiments suggest auranofin would be 10 times more effective than metronidazole, the current medication for amoebic infection, which means that it could be used in very small doses or even as a one-off tablet. Better still, the drug has ...

RA drug effective against Entamoeba histolytica - News-Medical.Net

"In our studies in animal models, auranofin was ten times more potent against this parasite than metronidazole." In a mouse model of amebic colitis and a hamster model of amebic liver abscess, the drug markedly decreased the number of parasites ...

Drug Found for Parasite That Is Major Cause of Death Worldwide - Newswise

It is listed by the National Institutes of Health as a category B priority biodefense pathogen. Current treatment relies on metronidazole, which has adverse effects, and potential resistance to the drug is an increasing concern. “Because auranofin has ...